Gamma Knife Radiosurgery (GKRS) is a non-invasive stereotactic radiotherapy technique that delivers high-dose radiation precisely to intracranial lesions, minimizing damage to surrounding healthy tissue.

Since the establishment of our Gamma Knife Center in 2003, we have accumulated experience in over 3,000 cases, treating a wide range of patients with brain tumors, vascular malformations, and functional disorders. By integrating preoperative imaging (MRI, CT) with a stereotactic frame or customized mask, most treatments can be completed on the same day, significantly reducing hospital stays and postoperative complication risks, while offering a safer, more effective, and minimally invasive treatment option.

• Clinical Outcomes

1. Case distribution: 47% benign tumors, 32% malignant tumors, 16% vascular lesions
2. Patient age range: 6 to over 90 years old

• Representative outcomes

1. Benign tumor control rate up to 95%, particularly in cases such as vestibular schwannomas and meningiomas
2. Average cochlear dose maintained < 4 Gy, contributing to a hearing preservation rate of 89% at 1-year post-treatment

Journal Article

• Predictors of hearing outcomes following low-dose stereotactic radiosurgery in patients with vestibular schwannomas: A retrospective cohort review
  https://pubmed.ncbi.nlm.nih.gov/28892717/
• Focal conformal fractionated radiotherapy vs. radiosurgery for lung cancer patients with limited brain metastases
  https://pubmed.ncbi.nlm.nih.gov/33065779/
• Survival of brain metastatic patients treated with gamma knife radiosurgery alone
  https://pubmed.ncbi.nlm.nih.gov/22705456/
• Outcomes and cost-effectiveness of gamma knife radiosurgery and whole brain radiotherapy for multiple metastatic brain tumors
  https://pubmed.ncbi.nlm.nih.gov/19269828/
• Severe pneumocranium after gamma knife stereotactic radiosurgery for brain metastasis: A case report and literature review
  https://pubmed.ncbi.nlm.nih.gov/38847695/

Monitoring mechanism

• Routine MRI follow-ups every 6 months for up to 5 years
• Outpatient follow-up to monitor for seizures, endocrine dysfunction, and psychiatric symptoms
• Utilization of the High-Definition Motion Management (HDMM) system to detect subtle patient movements with mask-based treatments
• Lightning planning system for automated dose optimization, enhancing selectivity and target coverage
• Icon Onsite Training provided to ensure optimal clinical application

Contact window

Department of Neurosurgery 018914@tool.caaumed.org.tw