醫師介紹
醫師學術論文
Paper
劉哲育 Jer-Yuh Liu 研究員
劉哲育研究員主要專長是研究兩個轉錄基因 (MZF-1/ELK-1) 互相結合與癌症惡化的機制研究,目前正在申請抗癌藥物篩選專利。第二專長是研究中草藥七層塔水萃取物的功效,尤其對於減肥美白、降低膽固醇、抗癌和降低抗癌藥物毒性等功效的研究,目前已有市售產品 (名稱為七層塔茶)。
相關連結
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | (Chen-Cheng Huang)、(Jin-Ming Hwang)、(Jen-Hsiang Tsai)、(Jing Huei Chen)、(Ho Lin)、(Geng-Jhih Lin)、楊新玲(Hsin-Ling Yang)、劉哲育(Jer-Yuh Liu)*、(Chiou-Ying Yang)*、(Je-Chiuan Ye)*,Aqueous Ocimum gratissimum extract induces cell apoptosisin human hepatocellular carcinoma cells,International Journal of Medical Sciences,2020 Jan,17(3):338-348 | 2020 . 01 |
2 | (Ping-Hung Lin)、(Shin-Mei Lee)、(Fang-LingTsai)、(Hsueh-Hui Lee)、(Kuanghui Hsieh)、(Yi-Fong Wang)、劉哲育(Jer-Yuh Liu)*、(Yieng-How Chen)*、(Je-Chiuan Ye)*,Enhanced immune capability of white Roman geese by Ocimum gratissimum,Zeitschrift fur Arznei- & Gewurzpflanzen,2019 Dec,23(4):160-165 | 2019 . 12 |
3 | (You-Cheng Hseu)、(Yu?Chi Huang)、(Varadharajan Thiyagarajan)、(Dony Chacko Mathew)、(Kai?Yuan Lin)、(Ssu?Ching Chen)、劉哲育(Jer-Yuh Liu)、(Li?Sung Hsu)、(Mei?Ling Li)、楊新玲(Hsin-Ling Yang)*,Anticancer activities of chalcone flavokawain B from Alpinia pricei Hayata in human lung adenocarcinoma (A549) cells via induction of reactive oxygen species-mediated apoptotic and autophagic cell death,JOURNAL OF CELLULAR PHYSIOLOGY,2019 Oct,234(10):17514-17526 | 2019 . 10 |
4 | (CHIA-HERNG YUE)、劉哲育(Jer-Yuh Liu)、(CHING-SHIANG CHI)、(CHING-WEN HU)、(KOK-TONG TAN)、(FU-MEI HUANG)、(YING-RU PAN)、(KUN-I LIN)、(CHIA-JEN LEE)*,Myeloid Zinc Finger 1 (MZF1) Maintains the Mesenchymal Phenotype by Down-regulating IGF1R/p38 MAPK/ER alpha Signaling Pathway in High-level MZF1-expressing TNBC cells,ANTICANCER RESEARCH,2019 Aug,39(8):4149-4164 | 2019 . 08 |
5 | (TSAI-KUN WU)、(CHUNG-HUNG CHEN)、(YING-RU PAN)、(CHING-WEN HU)、(FU-MEI HUANG)、劉哲育(Jer-Yuh Liu)、(CHIA-JEN LEE)*,Cetrimonium Bromide Inhibits Cell Migration and Invasion of Human Hepatic SK-HEP-1 Cells Through Modulating the Canonical and Non-canonical TGF-β Signaling Pathways,ANTICANCER RESEARCH,2019 Jul,39(7):3621-3631 | 2019 . 07 |
6 | (Julia Huei-Mei Chang)、林志學(Chih-Hsueh Lin)、徐布(SHIBU MARTHANDAM ASOKAN)、(Yung-Chen Chou)、劉哲育(Jer-Yuh Liu)、(Yen-Hong Chou)、(Chia-Yao Shen)、(Yu-Lan Yeh)、(Vijaya Padma Viswanadha)、黃志揚(Chih-Yang Huang)*,Cryptotanshinone (Dsh-003) from Salvia miltiorrhiza Bunge inhibits prostaglandin E2-induced survival and invasion effects in HA22T hepatocellular carcinoma cells,ENVIRONMENTAL TOXICOLOGY,2018 Sep,32(12): | 2018 . 09 |
7 | (Yieng-How Chen)、(Shin-Mei Lee)、(Jenn-Chung Hsu)、(Shyi-Kuen Yang)、(Pei-Yu Chao)、劉哲育(Jer-Yuh Liu)*、(Ping-Hung Lin)*、(Je-Chiuan Ye)*,Effects of Sorghum Distillery Residue Supplemented with Ocimum gratissimum on Erythrocyte Profiles, Egg Traits, and Immunity of Laying Hens,Zeitschrift fur Arznei- & Gewurzpflanzen,2018 Jun,22(2):91-97 | 2018 . 06 |
8 | (JI-KUEN YU)、(CHIA-HERNG YUE)、(YING-RU PAN)、(YUNG-WEI CHIU)、劉哲育(Jer-Yuh Liu)、(KUN-I LIN)*、(CHIA-JEN LEE)*,Isochlorogenic Acid C Reverses Epithelial–Mesenchymal Transition via Down-regulation of EGFR Pathway in MDA-MB-231 cells,ANTICANCER RESEARCH,2018 Apr,38():2127-2135 | 2018 . 04 |
9 | (Jin-Sun Lee)、(Yuh-Yih Lin)、(Tsu-Shing Wang)、劉哲育(Jer-Yuh Liu)、(Wei-Wen Lin)、(Jaw-Ji Yang)*,Antitumorigenic Effects of ZAK beta, an Alternative Splicing Isoform of ZAK,CHINESE JOURNAL OF PHYSIOLOGY,2018 Mar,61(1):25-34 | 2018 . 03 |
10 | (Je-Chiuan Ye)、(Li-Sung Hsu)、(Jen-Hsiang Tsai)、楊新玲(Yang, Hsin-ling)、(Meen-Woon Hsiao)、(Jin-Ming Hwang)、(Chia-Jen Lee)*、劉哲育(Liu, Jer-Yuh)*,MZF-1/Elk-1/PKCα is associated with poor prognosis in patients with hepatocellular carcinoma,Journal of Cancer,2017 Sep,8(15):3028-3036 | 2017 . 09 |
11 | (Hui-Min Wang)、楊新玲(Yang Hsin-ling)、(Varadharajan Thiyagarajan)、(Tzu-Hsiang Huang)、(Pei-Jane Huang)、(Ssu-Ching Chen)、劉哲育(Liu Jer-Yuh)、(Li-Sung Hsu)、(Hsueh-Wei Chang)、許游章(You-Cheng Hseu)*,Coenzyme Q0 Enhances Ultraviolet B–Induced Apoptosis in Human Estrogen Receptor–Positive Breast (MCF-7) Cancer Cells,INTEGRATIVE CANCER THERAPIES,2017 Sep,16(3):385-396 | 2017 . 09 |
12 | 許游章(Hseu, You-Cheng)、(Tai-Jung Tsai)、(Mallikarjuna Korivi)、劉哲育(Liu, Jer-Yuh)、陳慧婕(Chen, Hui-Jye)、(Chung-Ming Lin)、(Yi-Chun Shen)、楊新玲(Yang, Hsin-ling)*,Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy,Scientific Reports,2017 Aug,7(1):8062 | 2017 . 08 |
13 | 趙佩玉(Chao, Pei-Yu)、(Tsay-I Chiang,)、(I-Chang Chang)、(Fang-Ling Tsai)、(Hsueh-Hui Lee)、(Kuanghui Hsieh)、(Yung-Wei Chiu)、(Te-Jen Lai)、劉哲育(Liu Jer-Yuh)*、(Li-Sung Hsu)*、(Yang-Chia Shih)*,Amelioration of estrogen-deficiency-induced obesity by Ocimum gratissimum,International Journal of Medical Sciences,2017 Jul,14(9):896-901 | 2017 . 07 |
14 | 趙佩玉(Chao, Pei-Yu)、(James A. Lin)、(Jin-Ming Hwang)、(Wei-Jen Ting)、黃志揚(Chih-Yang Huang)*、劉哲育(Liu Jer-Yuh)*,Attenuation of Oxidative Stress-Induced Cell Apoptosis in Schwann RSC96 Cells by Ocimum Gratissimum Aqueous Extract,International Journal of Medical Sciences,2017 Jul,14(8):764-771 | 2017 . 07 |
15 | (Jen-Hsiang Tsai)、劉哲育(Liu Jer-Yuh)*,Pharmacological Studies on the Aqueous Leave Extract of Ocimum Gratissimum L.,Adaptive Medicine,2017 Mar,9(1):23-27 | 2017 . 03 |
16 | (Chia-Ting Chang)、(Mallikarjuna Korivi)、黃慧琪(Hui-Chi Huang)、(Varadharajan Thiyagarajan)、(Kai-Yuan Lin)、(Pei-Jane Huang)、劉哲育(Liu Jer-Yuh)、許游章(You-Cheng Hseu)*、楊新玲(Yang Hsin-ling)*,Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells,FOOD AND CHEMICAL TOXICOLOGY,2017 Feb,103(-):1-17 | 2017 . 02 |
17 | (Chia-Ting Chang)、許游章(You-Cheng Hseu)、(Varadharajan Thiyagarajan)、黃慧琪(Hui-Chi Huang)、(Li- Sung Hsue)、(Pei-Jane Huang)、劉哲育(Liu Jer-Yuh)、(Jiunn-Wang Liao)、楊新玲(Yang Hsin-ling)*,Antrodia salmonea induces G2 cell-cycle arrest in human triple-negative breast cancer (MDA-MB-231) cells and suppresses tumor growth in athymic nude mice,JOURNAL OF ETHNOPHARMACOLOGY,2017 Jan,196(20):9-19 | 2017 . 01 |
18 | (Tsay-I Chiang)、(I-Chang Chang)、(Hsueh-Hui Lee)、(Kuang hui Hsieh)、(Yung-Wei Chiu)、(Te-Jen Lai)、劉哲育(Liu Jer-Yuh)*、(Li-Sung Hs)*、(Shao-Hsuan Kao)*,Amelioration of estrogen deficiency-induced obesity by collagen hydrolysate,International Journal of Medical Sciences,2016 Nov,13(11):853-857 | 2016 . 11 |
19 | 趙佩玉(Chao, Pei-Yu)、林子恩(Lin, Tzu-En)、丁偉仁(Wei-Jen Ting)、(Hsueh-Hui Lee)、(Kuanghui Hsieh)、(Yung-Wei Chiu)、(Te-Jen Lai)、(Jin-Ming Hwang)*、劉哲育(Liu Jer-Yuh)*、黃志揚(Chih-Yang Huang)*,Ocimum gratissmum aqueous extract reduces plasma lipid in hypercholesterol-fed hamsters,International Journal of Medical Sciences,2016 Nov,13(11):819-824 | 2016 . 11 |
20 | (Chia-Herng Yue)、劉良智(Liu, Liang-Chih)、(Erl-Shyh Kao)、(Ho Lin)、(Li-Sung Hsu)、(Chih-Wei Hsu)、(Yu-Yu Lin)、(Yi-Syuan Lin)、劉哲育(Liu Jer-Yuh)*、(Chia-Jen Lee)*,Protein kinase C α involved in the regulation of AXL receptor tyrosine kinase expression in triple-negative breast cancer cells.,Molecular Medicine Reports,2016 Aug,2016(14):1636-1646 | 2016 . 08 |
21 | (Chia-Jen Lee)、(Li-Sung Hsu)、(Chia-Herng Yue)、(Ho Lin)、(Yung-Wei Chiu)、(Yu-Yu Lin)、黃志揚(Chih-Yang Huang)*、洪明奇(Mien-Chie Hung)*、劉哲育(Liu Jer-Yuh)*,MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells,Oncotarget,2016 Aug,7(37):5985-59859 | 2016 . 08 |
22 | (En-Hui Cheng)、劉哲育(Liu Jer-Yuh)、(Tsung-Hsein Lee)、(Chun-Chia Huang)、(Chung-I Chen)、(Lii-Sheng Huang)、(Maw-Sheng Lee)*,Requirement of leukemia inhibitory factor or epidermal growth factor for pre-implantation embryogenesis via JAK/STAT3 signaling pathways,PLoS One,2016 Apr,11(4):e0153086 | 2016 . 04 |
23 | (Wen-Hong Wang)、(Yung-Wei Chiu)、(Shao-Hsuan Kao)、(Wei-Jen Ting)、(Chih-Yin Hsu)、(Hung-Hui Cheng)、(Hsueh-Hui Lee)、(Kuanghui Hsieh)*、劉哲育(Liu Jer-Yuh)*、(Jin-Ming Hwang)*,Eight Probiotics Effective in Lowering Serum Lipids,Adaptive Medicine,2016 Mar,8(1):1-5 | 2016 . 03 |
24 | (I-Chang Chang)、(Tsay-I Chiang)、(Chun Lo)、(Yi-Hua Lai)、(Chia-Herng Yue)、劉哲育(Liu Jer-Yuh)*、(Li-Sung Hsu)*、(Chia-Jen Lee)*,Anemone altaica induces apoptosis in human osteosarcoma cells.,AMERICAN JOURNAL OF CHINESE MEDICINE,2015 Jul,43(5):1-12 | 2015 . 07 |
25 | (Chia-Herng Yue)、黃志揚(Chih-Yang Huang)、(Jen-Hsiang Tsai)、(Chih-Wei Hsu)、(Yi-Hsien Hsieh)*、(Ho Lin)*、劉哲育(Liu Jer-Yuh)*,MZF-1/Elk-1 complex binds to protein kinase Cα promoter and is involved in hepatocellular carcinoma,PLoS One,2015 May,10(5):e0127420 | 2015 . 05 |
26 | (Yieng-How Chen)、(Yung-Wei Chiu)、(Jyh-Cherng Shyu)、(Chin-Chiu Tsai)、(Hsueh-Hui Lee)、(Chuan-Chen Hung)、(Jin-Ming Hwang)*、劉哲育(Liu Jer-Yuh)*、(Wen-Hong Wang)*,Protective Effects of Ocimum gratissimum Polyphenol Extract on Carbon Tetrachloride-Induced Liver Fibrosis in Rats.,CHINESE JOURNAL OF PHYSIOLOGY,2015 Feb,58(1):55-63 | 2015 . 02 |
27 | (CHIA-JEN LEE)、(CHIA-HERNG YUE)、(YU-JIE LIN)、(YU-YU LIN)、(SHAO-HSUAN KAO)*、劉哲育(Liu Jer-Yuh)*、(YIENG-HOW CHEN)*,Antitumor Activity of Acriflavine in Lung Adenocarcinoma Cell Line A549,ANTICANCER RESEARCH,2014 Nov,34(11):6467-6472 | 2014 . 11 |
28 | (ALEX CHIEN HWA LIAO)、(CHIA-CHENG KUO)、(YEI-CHUNG HUANG)、(CHI-WEI YEH)、許游章(You-Cheng Hseu)、劉哲育(Liu Jer-Yuh)*、(LI-SUNG HSU)*,Naringenin inhibited migration of bladder cancer cells via downregulation of AKT and MMP-2.,Molecular Medicine Reports,2014 Aug,10(8):1531-1536 | 2014 . 08 |
29 | (CHIA-JEN LEE)、(CHIA-HERNG YUE)、林俞佑(YU-YU LIN)、(JAW-CHING WU)*、劉哲育(Liu Jer-Yuh)*,Antitumor Activity of Acriflavine in Human Hepatocellular Carcinoma Cells,ANTICANCER RESEARCH,2014 Jul,34(7):3549-3556 | 2014 . 07 |
30 | (Yieng-How Chen)、(Shin-Mei Lee)、(Fang-Ling Tsai)、(Hsueh-Hui Lee)、劉哲育(Liu Jer-Yuh)*,Dietary Supplementation of Ocimum Gratissimum Improves Immune Response without Affecting the Growth Performance and Blood Characteristics in Taiwan Country Chicken,JOURNAL OF POULTRY SCIENCE,2014 May,51(1):313-320 | 2014 . 05 |
31 | (Yung-Wei Chiu)、趙佩玉(Pei-Yu Chao)、(Chin-Chiu Tsai)、(Hui-Ling Chiou)、(Yuh-Chyan Liu)、(Chuan-Chen Hung)、(Hung-Che Shih)、(Te-Jen Lai)*、劉哲育(Liu Jer-Yuh)*,Ocimum gratissimum is Effective in Prevention against Liver Fibrosis In Vivo and In Vitro,AMERICAN JOURNAL OF CHINESE MEDICINE,2014 Apr,42(4):833-852 | 2014 . 04 |
32 | (Yi-Chun Lin)、(Kuei-Mei Cheng)、Hsin-Yu Huan、趙佩玉(Pei-Yu Chao)、(Jin-Ming Hwang)、(Hsueh-Hui Lee)、(Cheng-You Lu)、(Yung-Wei Chiu)*、劉哲育(Liu Jer-Yuh)*,Hepatoprotective activity of Chhit-Chan-Than extract powder against carbon tetrachloride-induced liver injury in rats,JOURNAL OF FOOD AND DRUG ANALYSIS,2014 Mar,22(3):220-229 | 2014 . 03 |
33 | (Chien-Chung Lin)、趙佩玉(Pei-Yu Chao)、(Chia-Yao Shen)、(Jyuan-Jen Shu)、(Shiow-Kang Yen)*、黃志揚(Chih-Yang Huang)*、劉哲育(Liu Jer-Yuh)*,Novel Target Genes Responsive to Apoptotic Activity by Ocimum gratissimum Extracts in Human Osteosarcoma cells,AMERICAN JOURNAL OF CHINESE MEDICINE,2014 Mar,42(3):743-767 | 2014 . 03 |
34 | (Hsiao-Chuan Chang)、(Yung-Wei Chiu)、(Yueh-Min Lin)、(Ray-Jade Chen)、(James A. Lin)、蔡輔仁(Fuu-Jen Tsai)、蔡長海(Chang-Hai Tsai)、郭昱君(Yu-Chun Kuo)、劉哲育(Liu Jer-Yuh)*、黃志揚(Chih-Yang Huang)*,Herbal Supplement Attenuation of Cardiac Fibrosis in Rats with CCl4-Induced Liver Cirrhosis,CHINESE JOURNAL OF PHYSIOLOGY,2014 Feb,57(): | 2014 . 02 |
35 | (YUNG-WEI CHIU)、(HUNG-JEN LO)、(HSIN-YU HUANG)、(PEI-YU CHAO)、(JIN-MING HWANG)、(PEI-YUN HUANG)、(SHYH-JER HUANG)、劉哲育(Liu Jer-Yuh)*、(TE-JEN LAI)*,Antioxidant and Cytoprotective Activities of Ocimum Gratissimum Extracts against Hydrogen Peroxide Induced Toxicity in Human HepG2 Cells,JOURNAL OF FOOD AND DRUG ANALYSIS,2013 Dec,():1-8 | 2013 . 12 |
36 | 劉哲育(Liu Jer-Yuh)、(Yi-Ching Chen)、(Chun-Hsiang Lin)、(Shao-Hsuan Kao)*,Perilla frutescens leaf extract inhibits mite major allergen Der p 2-induced gene expression of pro-allergic and pro-inflammatory cytokines in human bronchial epithelial cell.,PLoS One,2013 Oct,8(10):e77458-e77458 | 2013 . 10 |
37 | 周詠欽(Yeong-Chin Jou)、(Yung-Wei Chiu)、(Yieng-How Chen)、(Jin-Ming Hwang)、(Pei-Yu Chao)、(Jiuan-Jen Shiu)、(Wen-Hung Hwang)、劉哲育(Liu Jer-Yuh)*、許立松(Li-Sung Hsu)*,Expression of Protein Kinase C α and the MZF-1 and Elk-1 Transcription Factors in Human Bladder Transitional Cell Carcinoma Cells,CHINESE JOURNAL OF PHYSIOLOGY,2012 Mar,55(2):75-81 | 2012 . 03 |
38 | 林岳民(Yueh-Min Lin)、(Cheng-Chuan Su)、(Wei-Wen Su)、(Jin-Ming Hwang)、(Hsi-Hsien Hsu)、蔡長海(Chang-Hai Tsai)、蔡輔仁(Fuu-Jen Tsai)、黃志揚(Chih-Yang Huang)*、劉哲育(Liu Jer-Yuh)*、陳立民(Li-Mien Chen)*,Expression of protein kinase C isoforms in cancerous breast tissue and adjacent normal breast tissue,CHINESE JOURNAL OF PHYSIOLOGY,2012 Feb,55(1):55-61 | 2012 . 02 |
39 | 于家珩(Chia-Herng Yue)、(Yung-Wei Chiu)、(Jai-Nien Tung)、(Bor-Show Tzang)、(Jiuan-Jen Shiu)、(Wen-Hung Huang)、劉哲育(Liu Jer-Yuh)*、黃俊銘(Jin-Ming Hwang)*,The Expression of Protein Kinase C α and the MZF-1 and Elk-1 Transcription Factors in Human Breast Cancer Cells,CHINESE JOURNAL OF PHYSIOLOGY,2012 Feb,55(1):31-36 | 2012 . 02 |
40 | (Chun-Ching Chiu,)、黃志揚(Chih-Yang Huang)、(Tzy-Yen Chen)、(Shao-Hsuan Kao)、劉哲育(Liu Jer-Yuh)、(Yi-WenWang)、(Bor-Show Tzang)、(Tsai-Ching Hsu)*,Beneficial Effects of Ocimum gratissimum Aqueous Extract on Rats with CCl4-Induced Acute Liver Injury,Evidence-based Complementary and Alternative Medicine,2012 ,1(1):1-9 | 2012 . |
41 | 李秉純(Ping-Chun Li)、(Yung-Wei Chiu)、(Yueh-Min Lin)、(Cecilia Hsuan Day)、(Guang-Yuh Hwang)、(Peiying Pai)、蔡輔仁(Fuu-Jen Tsai)、蔡長海(Chang-Hai Tsai)、(Yu-Chun Kuo)、(Hsiao-Chuan Chang)、劉哲育(Liu Jer-Yuh)*、黃志揚(Chih-Yang Huang)*,Herbal Supplement Ameliorates Cardiac Hypertrophy in Rats with CCl 4 -Induced Liver Cirrhosis,Evidence-based Complementary and Alternative Medicine,2012 ,1(1):1-9 | 2012 . |
42 | 邱永偉(Yung-Wei Chiu)、謝逸憲(Yi-Hsien Hsieh)、劉哲育(Liu Jer-Yuh)*,Protein Kinase C Alpha Expression in Human Hepatocellular Carcinoma,Adaptive Medicine,2011 Mar,3(1):11-15 | 2011 . 03 |
43 | 陳翰民(Han-Min Chen)、(Mu-Jang Lee)、(Cheng-Yi Kuo)、(Pei-Lin Tsai)、劉哲育(Liu Jer-Yuh)、高紹軒(Shao-Hsuan Kao)*,Ocimum gratissimum Aqueous Extract Induces Apoptotic Signalling in Lung Adenocarcinoma Cell A549,Evidence-based Complementary and Alternative Medicine,2010 Sep,2011(2011):739093-739093 | 2010 . 09 |
44 | 李木壤(Mu-Jang Lee)、(Han-Min Chen)、(Bor-Show Tzang)、(Chiu-Wen Lin)、(Chau-JongWang)、劉哲育(Liu Jer-Yuh)*、高紹軒(Shao-Hsuan Kao)*,Ocimum gratissimum Aqueous Extract Protects H9c2Myocardiac Cells from H2O2-Induced Cell Apoptosis through Akt Signalling,Evidence-based Complementary and Alternative Medicine,2010 Aug,2011(2011):578060-578060 | 2010 . 08 |
45 | 蔡仁祥(Jen-Hsiang Tsai)、陳暉雯(Haw-Wen Chen)、陳藝婉(Yi-Wan Chen)、劉哲育(Liu Jer-Yuh)*、李宗貴(Chong-Kuei Lii)*,The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT,JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY,2010 May,2010(2010):486267-486267 | 2010 . 05 |
46 | 林建中(Chien-Chung Lin)、黃俊銘(Jin-Ming Hwang)、(Min-Ting Tsai)、(Wei-Wen Su)、(Li-Ming Chen)、賴東淵(Tung-Yuan Lai)、(Hsi-Hsien Hsu)、(Shiow-Kang Yen)*、黃志揚(Chih-Yang Huang)*、劉哲育(Liu Jer-Yuh)*,Protein kinase C alpha location and the expression of phospho-MEK and MDR1 in hepatitis virus-related hepatocellular carcinoma biopsies,CHINESE JOURNAL OF PHYSIOLOGY,2010 Apr,53(2):112-118 | 2010 . 04 |
47 | 蔡仁祥(Jen-Hsiang Tsai)、黃俊銘(Jin-Ming Hwang)、應宗和(Tsung-Ho Ying)、徐志誠(Jyh-Cherng Shyu)、蔡金秋(Chin-Chiu Tsai)、謝易修(Yih-Shou Hsieh)、王意維(Yi-Wei Wang)、劉哲育(Liu Jer-Yuh)*、高紹軒(Shao-Hsuan Kao)*,The activation of matrix metalloproteinase-2 induced by protein kinase C alpha in decidualization.,JOURNAL OF CELLULAR BIOCHEMISTRY,2009 Oct,108(3):547-554 | 2009 . 10 |
48 | 黃俊銘(Jin-Ming Hwang)、高紹軒(Shao-Hsuan Kao)、謝易憲(Yi-Hsien Hsieh)、李琨林(Kuen-Lin Li)、王佩璽(Pei-Hsi Wang)、許立松(Li-Song Hsu)、劉哲育(Liu Jer-Yuh)*,Reduction of anion exchanger 2 expression induces apoptosis of human hepatocellular carcinoma cells,MOLECULAR AND CELLULAR BIOCHEMISTRY,2009 Jul,327(1-2):135-144 | 2009 . 07 |
49 | (Tsung-Ho Ying)、(Jen-Hsiang Tsai)、(Trang-Tiau Wu)、(Min-Ting Tsai)、(Wei-Wen Su)、(Yih-Shou Hsieh)、劉哲育(Liu Jer-Yuh)*,Immunochemical localization of protein kinase Cα in the biopsies of human hepatocellular carcinoma,CHINESE JOURNAL OF PHYSIOLOGY,2008 Oct,51(5):269-274 | 2008 . 10 |
50 | (Tsung-Ho Ying)、(Yi-Hsien Hsieh)、(Yih-Shou Hsieh)、劉哲育(Liu Jer-Yuh)*,Antisense oligonucleotide Elk-1 suppresses the tumorigenicity of human hepatocellular carcinoma cells,CELL BIOLOGY INTERNATIONAL,2008 Feb,32(2):210-216 | 2008 . 02 |
51 | 劉忠榮(Chung-Jung Liu)、黃俊銘(Jin-Ming Hwang)、巫堂鎥(Trang-Tiau Wu)、謝易憲(Yi-Hsien Hsieh)、吳誠中(Cheng-Chung Wu)、謝易修(Yih-Shou Hsieh)、蔡長海(Chang-Hai Tsai)、(Hsi-Chin Wu)、黃志揚(Chih-Yang Huang)*、劉哲育(Liu Jer-Yuh)*,Anion exchanger inhibitor DIDS induces human poorly-differentiated malignant hepatocellular carcinoma HA22T cell apoptosis.,MOLECULAR AND CELLULAR BIOCHEMISTRY,2008 Jan,308(1-2):117-125 | 2008 . 01 |
52 | 巫堂鎥(Trang-Tiau Wu)、謝易憲(Yi-Hsien Hsieh,)、謝易修(Yih-Shou Hsieh)、劉哲育(Liu Jer-Yuh)*,Reduction of PKCα Decreases Cell Proliferation, Migration, and Invasion of Human Malignant Hepatocellular Carcinoma,JOURNAL OF CELLULAR BIOCHEMISTRY,2008 Jan,103(1):9-20 | 2008 . 01 |
53 | (Trang-Tiau Wu)、(Yi-Hsien Hsieh)、(Cheng-Chung Wu)、(Yih-Shou Hsieh)、黃志揚(Chih-Yang Huang)、劉哲育(Liu Jer-Yuh)*,Overexpression of protein kinase Cα mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis,CLINICA CHIMICA ACTA,2007 Jul,382(1-2):54-58 | 2007 . 07 |
54 | 謝逸憲(Yi-Hsien Hsieh)、巫堂鎥(Trang-Tiau Wu)、黃志揚(Chih-Yang Huang)、謝易修(Yih-Shou Hsieh)、黃俊銘(Jin-Ming Hwang)、劉哲育(Liu Jer-Yuh)*,p38 MAPK Pathway Is Involved in Protein Kinase Cα-Regulated Invasion in Human Hepatocellular Carcinoma Cells.,CANCER RESEARCH,2007 May,67(9):4320-4327 | 2007 . 05 |
55 | (Yi-Hsien Hsieh)、(Trang-Tiau Wu)、黃志揚(Chih-Yang Huang)、(Yih-Shou Hsieh)、劉哲育(Liu Jer-Yuh)*,Antisense Suppression of Tumorigenicity of Human Hepatocellular Carcinoma Cells by Antisense Oligonucleotide MZF-1,CHINESE JOURNAL OF PHYSIOLOGY,2007 Apr,50(1):9-15 | 2007 . 04 |
56 | (Trang-Tiau Wu)、(Yi-Hsien Hsieh)、(Cheng-Chung Wu)、(Jen-Hsiang Tsai)、(Yih-Shou Hsieh)、黃志揚(Chih-Yang Huang)、劉哲育(Liu Jer-Yuh)*,Overexpression of Anion Axchanger 2 in Human Hepatocellular Carcinoma,CHINESE JOURNAL OF PHYSIOLOGY,2006 Aug,49(4):192-198 | 2006 . 08 |
57 | 郭薇雯(Wei-Wen Kuo)、劉忠榮(Liu, Chung-Jung)、(Chen, Li-Ming)、吳介信(Chieh-Hsi Wu)、朱俊憲(Chu, Chun-Hsien)、劉哲育(Liu Jer-Yuh)、(Lu, Min-Chi)、林子恩(Lin, Tzu-En)、李信達(Shin-Da Lee)*、黃志揚(Chih-Yang Huang)*,Cardiomyocyte apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II.,APOPTOSIS,2006 May,11(5):1075-1089 | 2006 . 05 |
58 | 劉哲育(Liu Jer-Yuh)、(Chang-Che Chen)、(Wen-Hong Wang)、(Jeng-Dong Hsu)、(Mon-Yuan Yang)、(Chau-Jong Wang)*,The protective effects of Hibiscus sabdariffa extract on CCl4-induced liver fibrosis in rats,FOOD AND CHEMICAL TOXICOLOGY,2006 Mar,44(3):336-343 | 2006 . 03 |
59 | (Yi-Hsien Hsieh)、(Trang-Tiau Wu)、(Jen-Hsiang Tsai)、黃志揚(Chih-Yang Huang)、(Yih-Shou Hsieh)、劉哲育(Liu Jer-Yuh)*,PKCα expression regulated by Elk-1 and MZF-1 in human HCC cells,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2006 Jan,339(1):217-225 | 2006 . 01 |
60 | (Jen-Hsiang Tsai)、(Min-Ting Tsai)、(Wei-Wen Su)、(Yao-Li Chen)、(Trang-Tiau Wu)、(Yih-Shou Hsieh)、黃志揚(Chih-Yang Huang)、(Kun-Tu Yeh)、劉哲育(Liu Jer-Yuh)*,Expression of protein kinase C alpha in biopsies and surgical specimens of human hepatocellular carcinoma.,CHINESE JOURNAL OF PHYSIOLOGY,2005 Sep,48(3):139-143 | 2005 . 09 |
61 | (Whei-Ling Chiang)、劉哲育(Liu Jer-Yuh)、(Chu-Yu Liao)、(Shun-Fa Yang)、(Yih-Shou Hsieh)、(Shu-Chen Chu)*,Alternation of cytosolic carbonic anhydrase isoenzymes during deciduomatal development in pregnant mice,FERTILITY AND STERILITY,2004 Oct,82(Suppl 3):1095-1100 | 2004 . 10 |
62 | (Tzu-Chun Cheng)、(Chun-Chia Huang)、(Chung-I Chen)、(Chung-Hsien Liu)、(Yih-Shou Hsieh)、黃志揚(Chih-Yang Huang)、(Maw-Sheng Lee)*、劉哲育(Liu Jer-Yuh)*,Leukemia Inhibitory Factor Antisense Oligonucleotide Inhibits the Development of Murine Embryos at Pre-Implantation Stages.,BIOLOGY OF REPRODUCTION,2004 May,70(5):1270-1276 | 2004 . 05 |
63 | (Tzu-Chun Cheng)、(Chun-Chia Huang)、(Lii-Sheng Huang3,)、(Chung-I Chen)、李茂盛(Maw-Sheng Lee)、劉哲育(Liu Jer-Yuh)*,Evaluation of Mouse Blastocyst Implantation Rate by Morphology Grading,CHINESE JOURNAL OF PHYSIOLOGY,2004 Mar,47(1):43-47 | 2004 . 03 |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | Hyper- phosphate levels in H9C2 cardiomyoblasts trigger cellular apoptosis via autophagy,106學年度研發日暨中亞聯大合作學術研討會,亞洲大學,2018.06.14~2018.06.14, | 2018 . 06 |
2 | Mechanism Of ResveratrolInhibit MitophagyTo Alleviate Aging Process,第44屆國軍軍醫學術研討會,國防醫學院,2017.11.24~2017.11.25, | 2017 . 11 |
3 | Down-regulated the metastatic function of β-catenin by Taiwanin C arecoline and 4NQO-induced oral cancer cells mediated through the GSK-3-β activation,105學年度研發日暨中亞聯大合作學術研討會(2017 China Asia Associated University (CAAU) Cooperative Academics Research Symposium),台中.亞洲大學,2017.04.25~2017.04.25, | 2017 . 04 |
4 | Resveratrol enhanced FOXO3 phosphorylation via synergetic activate SIRT-1 and PI3K/Akt signaling to benefit exercise effects in elderly rat hearts,中亞聯大兩校合作學術研討會,亞洲大學,2015.04.02~2015.04.02, | 2015 . 04 |
5 | Taiwanin C inhibits proliferation and enhances apoptosis of arecoline and 4-NQO-induced oral cancer cells via the suppression of EGFR/PI3K pathway,亞洲大學與中國醫藥大學兩校合作學術研討會,亞洲大學,2014.03.06~2014.03.06, | 2014 . 03 |
6 | Down-regulation of PKCNI inhibits AXL expression in human Triple-negative breast cancer cells,Kyoto Breast Cancer Consensus Conference 2014 International Convention,Miyako Kyoto,2014.02.20~2014.02.22, | 2014 . 02 |
7 | Decrease of PKC alpha expression by a TAT-fused peptide in human triple-negative breast cancer cells,Kyoto Breast Cancer Consensus Conference 2014 International Convention,Miyako Kyoto,2014.02.20~2014.02.22, | 2014 . 02 |
8 | 氣球擴張術傷害頸動脈誘發心肌細胞凋亡過程中心肌IGF-I存活訊息途徑代償機轉探討,2013年兩校合作學術研討會,亞洲大學,2013.03.13~2013.03.13, | 2013 . 03 |
9 | 七層塔葉萃取物對人類骨肉瘤細胞的抗腫瘤作用,第二屆海峽兩岸調適醫學及體適能學術研討會,山東濟南,2011.10.12~2011.10.17,七層塔葉萃取物對人類骨肉瘤細胞的抗腫瘤作用 | 2011 . 10 |
10 | 丁豎杇藉活化肝中之HCG、IGF-1及uPA訊息途徑來促進部分肝切除大鼠之肝再生能力,傳統中醫藥及中草藥醫學研討會,中國醫藥大學立夫教學大樓六樓第一會議室,2011.09.10~2011.09.10, | 2011 . 09 |
11 | 肝臟纖維化研究,歐洲肝臟研究學會(EASL)專題會議 (The 2011 European Association for the Study of the Liver Monothematic Conference,德國波昂(Bonn),2011.06.17~2011.06.18,七層塔萃取物對四氯化碳誘導大鼠肝纖維化的保護作用 | 2011 . 06 |
12 | Ocimun gratissimum Aqueous Extract Protects Schwann RSC96 cells from H2O2-Induced Cell Apoptosis,第二十六屆生物醫學聯合學術年會,國防醫學院,2011.03.19~2011.03.20, | 2011 . 03 |
13 | The Inhibitory Effect of Ocimum gratissimum Extracts on the Cell Growth and Cell Migration in Human Osteosarcoma,第二十六屆生物醫學聯合學術年會,國防醫學院,2011.03.19~2011.03.20, | 2011 . 03 |
14 | 攝取混合共生的數種益生菌調節血脂功效評估,台灣保健食品學會2011年會員大會暨保健食品與代謝症候群研討會,輔仁大學醫學院國璽樓國際會議廳,2011.02.11~2011.02.11,攝取混合共生的數種益生菌調節血脂功效評估 | 2011 . 02 |
15 | Schwann cell migration induced by earthworm extract via activation of PAs and MMP2/9 mediated through ERK1/2 and p38,第九屆國際蚯蚓生態學術研討會 (the 9th International Symposium of Earthworm Ecology),墨西哥 (Mexico) 韋拉克魯斯 (Veracruz) 哈拉帕市 (Xalapa),2010.09.05~2010.09.10, | 2010 . 09 |
16 | Regulation of Protein Kinase Cα Expression in Human Hepatocellular Carcinoma Cells by Direct Interaction of Myeloid Zinc Finger Gene (MZF-1) and Ets-Like Protein-1 (Elk-1),第八屆美國癌症研究學會及日本癌症學會聯合年會會議:癌症基因體、癌症外基因體及新藥研發,美國夏威夷唯客樂,2010.02.05~2010.02.09, | 2010 . 02 |
專書
暫無資料研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 個別型,CMU109-S-29,,本校(含附醫),七層塔提取物可減輕急性肺損傷,2020.11.2~2021.7.31 | 2020 . 11 |
2 | 個別型,DMR-110-083,劉哲育(Jer-Yuh Liu),附醫院內計畫,橙花醇對高血壓引起的H9c2細胞和自發性高血壓大鼠心臟炎症和纖維化的治療作用:TLR4 /NF-κB軸的前瞻性參與,2020.8.1~2021.7.31 | 2020 . 08 |
3 | 個別型,MOST 107-2320-B-039-025-MY3,,科技部,七層塔水萃物輔助抗癌藥物提高癌症化療的療效,2020.8.1~2021.7.31 | 2020 . 08 |
4 | 個別型,CMU108-S-43,,本校(含附醫),合併七層塔萃取液和高蛋白飲食改善鏈脲佐菌素誘導小鼠糖尿病之血糖平衡,2019.10.31~2020.7.31 | 2019 . 10 |
5 | 個別型,MOST 107-2320-B-039-025-MY3,,科技部,七層塔水萃物輔助抗癌藥物提高癌症化療的療效,2019.8.1~2020.7.31 | 2019 . 08 |
6 | 個別型,MOST 107-2320-B-039-025-MY3,,科技部,七層塔水萃物輔助抗癌藥物提高癌症化療的療效,2018.8.1~2019.7.31 | 2018 . 08 |
7 | 個別型,MOST 106-2320-B-039-022-,,科技部,七層塔水萃物透過調節凋亡因子和自噬作用緩解抗癌藥物的耐受性,2017.8.1~2018.7.31 | 2017 . 08 |
8 | 個別型,DMR-106-030,,附醫院內計畫,研究在人類三陰性乳癌細胞中MZF-1B活化之機制,2016.8.1~2017.7.31 | 2016 . 08 |
9 | 個別型,CMU104-S-41,,本校(含附醫),研究在人類三陰性乳腺癌細胞中MZF-1調控IGF-1R基因之機制,2015.11.11~2016.7.31 | 2015 . 11 |
10 | 個別型,MOST 104-2320-B-039-032,,科技部,三陰性乳腺癌細胞內Elk-1/MZF-1異源二聚體調控全基因組標靶基因之研究,2015.8.1~2016.7.31 | 2015 . 08 |
11 | 個別型,無,曾喜鵬、洪祺森、施養佳、李明明、蔡存孝、張嵐蘭、鄭聖時、丁崇德、黃志揚(Chih-Yang Huang)、劉哲育(Liu Jer-Yuh)、陳相訓,科技部,台灣茶產業產銷轉型技術推廣與服務(1/3),2015.2.1~2016.1.31 | 2015 . 02 |
12 | 個別型,DMR-104-019,劉良智(Liu, Liang-Chih),附醫院內計畫,研究在人類三陰性乳腺癌細胞中AXL 基因,2014.8.1~2015.7.31 | 2014 . 08 |
13 | 個別型,NSC 102-2320-B-039-049,,科技部,研究新的小分子在人乳腺癌中藉由調控轉錄因子Elk-1和MZF-1而抑制PKCα的表達,2013.8.1~2014.7.31 | 2013 . 08 |
14 | 整合型項下子計畫(主持人),NSC 99-2632-B-039-001-MY3,余永倫(Yung-Luen Yu)、蘇振良(Jen-Liang Su)、黃偉謙(Wei-Chien Huang)、李龍緣(Long-Yuan Li)、宋賢穎(Shian-Ying Sung)、謝嘉玲(Chia-Ling Hsieh)、劉哲育(Liu Jer-Yuh),科技部,腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2012.8.1~2013.7.31 | 2012 . 08 |
15 | 整合型(召集人、總主持人),NSC 99-2632-B-039-001-MY3,,科技部,腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2012.8.1~2013.7.31 | 2012 . 08 |
16 | 整合型(召集人、總主持人),NSC 99-2632-B-039-001-MY3,,科技部,腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2011.8.1~2012.7.31 | 2011 . 08 |
17 | 個別型,NSC 98-2320-B-039-042-MY3,,科技部,ELK-1和MZF-1轉錄因子參與調控癌瘤細胞中蛋白激酵素C ALPHA基因表現之研究,2011.8.1~2012.7.31 | 2011 . 08 |
18 | 整合型項下子計畫(主持人),NSC 99-2632-B-039-001-MY3,余永倫(Yung-Luen Yu)、蘇振良(Jen-Liang Su)、黃偉謙(Wei-Chien Huang)、李龍緣(Long-Yuan Li)、宋賢穎(Shian-Ying Sung)、謝嘉玲(Chia-Ling Hsieh)、劉哲育(Liu Jer-Yuh),科技部,腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2011.8.1~2012.7.31 | 2011 . 08 |
19 | 整合型(召集人、總主持人),NSC 100-2325-B-010 -003 -,劉哲育(Liu Jer-Yuh),科技部,建立和人類B型肝炎病毒感染類似的肝硬化與肝癌的小鼠模式並用以篩選具潛力的抗病毒與抗肝癌藥物-(總計畫與子計畫三)建立和人類B型肝炎病毒感染類似的肝硬化與肝癌的小鼠模式並用以篩選具潛力的抗病毒與抗肝癌藥物,2011.5.1~2014.4.30 | 2011 . 05 |
20 | 個別型,NSC 98-2320-B-039-042-MY3,,科技部,ELK-1和MZF-1轉錄因子參與調控癌瘤細胞中蛋白激酵素C ALPHA基因表現之研究,2010.8.1~2012.7.31 | 2010 . 08 |
21 | 整合型(召集人、總主持人),CMU99-NSC-09,李龍緣(Long-Yuan Li)、謝嘉玲(Chia-Ling Hsieh)、宋賢穎(Shian-Ying Sung)、余永倫(Yung-Luen Yu)、黃偉謙(Wei-Chien Huang)、蘇振良(Jen-Liang Su)、劉哲育(Liu Jer-Yuh),本校(含附醫),腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2010.8.1~2011.7.31 | 2010 . 08 |
22 | 整合型項下子計畫(主持人),NSC 99-2632-B-039-001-MY3,余永倫(Yung-Luen Yu)、蘇振良(Jen-Liang Su)、黃偉謙(Wei-Chien Huang)、李龍緣(Long-Yuan Li)、宋賢穎(Shian-Ying Sung)、謝嘉玲(Chia-Ling Hsieh)、劉哲育(Liu Jer-Yuh),科技部,腫瘤發展之訊息傳遞路徑-腫瘤發展之訊息傳遞路徑,2010.8.1~2011.7.31 | 2010 . 08 |
23 | 個別型,NSC 98-2320-B-039-042-MY3,,科技部,ELK-1和MZF-1轉錄因子參與調控癌瘤細胞中蛋白激酵素C ALPHA基因表現之研究,2009.8.1~2010.7.31 | 2009 . 08 |
24 | 個別型,CSMU-TTM-097-002,于家珩(Yue Chia-Herng),,人類乳癌細胞內蛋白激酵素C alpha基因調控的機制,2008.8.1~2009.7.31 | 2008 . 08 |
25 | 個別型,CSMU-CHA-097-001,周詠欽(Jou Yeong-Chin),,人類泌尿膀胱移行細胞癌細胞內蛋白激酵素C alpha基因調控的機制,2008.8.1~2009.7.31 | 2008 . 08 |
26 | 個別型,CSMU 96-OM-B-40,巫堂鎥(Wu Trang-Tiau),中山醫學大學,探討七層塔純化物的保肝作用,2007.10.1~2008.9.30 | 2007 . 10 |
27 | 個別型,NSC 95-2320-B-040-043,,科技部,人類肝細胞癌內蛋白激酵素C 異構體的異常功能與基因調節之研究,2006.8.1~2007.7.31 | 2006 . 08 |
專利技術
專利/Patent (專利名稱,專利類別,專利國別,專利號碼,專利期間) |
日期 | |
1 | 一種 具有抑制 MZF -1與 Elk -1交互作用 的醫藥組合物 醫,發明專利,台灣,I598105,2017.9.11~2035.6.14 | 2017 . 09 |
2 | 鷹不泊的萃取物及其製備方法與用途,發明專利,台灣,I409075,2013.9.21~2030.6.2 | 2013 . 09 |
3 | PRODUCT CONTAINING ESTRACT FROM ZANTHOXYLUM AVICENNAE(LAM.) DC., AND PREPARATION PROCESS AND USE THE,發明專利,美洲,US 8,409,632 B2,2011.8.19~2031.8.19 | 2011 . 08 |
獲獎事蹟
暫無資料技術轉移
技術轉移/Technology Transfer (技術名稱,發明人,合約期間,專利名稱,授權單位,授權單位名稱) |
日期 | |
1 | 七層塔萃取技術,劉哲育(Liu Jer-Yuh),2008.3~2008.11,,中山醫學大學,天賜爾生物科技股份有限公司 | 2008 . 03 |